13 Prayers for Anxiety and Depression

Prayers for anxiety and depression will help you in your time of great difficulty. Difficult circumstances in life can cause you to feel anxious and depressed.

This happens when you don’t know how to handle some situations that threaten your life.

Prayers for Anxiety and Depression
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According to an article on Crosswalk.com, anxiety, and depression stem from attempts to control either the future (through worrying) or the past (by trying to change what has happened).

Billy Graham said anxiety is the natural result when our hopes are centered on anything short of God and his will for us.

God’s word directs us to pray over everything instead of worrying about any situation (Philippians 4:6-7).

The result of praying instead of worrying is the promise of God’s peace that surpasses all understanding. It guards your heart and mind and this keeps you from anxiety and depression.

Below are 13 prayers for anxiety and depression.

#1 Prayer for God’s loving Words.

Proverbs 12:25 “Anxiety in the heart of man causes depression, But a good word makes it glad.”

Lord, I praise you for you are full of glory and majesty. You are my healer and deliverer and I can always count on you to be by my side.

I ask that you fill my mind with your words so that my heart may be glad.

Remove all anxiety from my heart and show me how to trust in you day by day. Help me not to worry about what tomorrow holds but to focus on today, which is the present.

You are in charge of my tomorrow and I know you have good plans for my life.

May the truth in your words fill my heart to overflowing.

In Jesus’ name, I pray. Amen.

#2 Prayer to be still and listen to God.

Psalm 46:10 “Be still, and know that I am God.”

Lord, thank you for the solutions for everything I go through in this life. You care about every aspect of my life and want to see me in good mental health.

When my mind is healthy, I can make sound decisions.

Help me to still my mind so I can hear you speaking to me. Your words always uplift my soul and give me hope for a better life.

Teach me to quiet my mind daily and identify your still small voice.

Give me the discernment I need to identify your voice from that of the stranger. I want to follow what you are saying to me.

In Jesus’ name, I pray. Amen.

#3 Prayer to discern the presence of God.

Isaiah 41:10 “So do not fear, for I am with you; do not be dismayed, for I am your God. I will strengthen you and help you; I will uphold you with my righteous right hand.”

Lord, I praise you because you are my helper and deliverer. Today I ask you to help me discern your presence in my life.

You promised that you are always with me at all times. I don’t have to fear because you are always watching over me.

Strengthen me to face each day without fear and anxiety. Help me overcome my depressing thoughts and only allow positive ones in my mind.

May your light shine on my path that I will see where I am going with clarity.

In Jesus’ name, I pray. Amen.

#4 Prayer for renewal of Hope.

Psalm 42:11 “Why, my soul, are you downcast? Why so disturbed within me? Put your hope in God, for I will yet praise him, my Savior and my God.”

Lord, my days are full of darkness. My soul is downcast and I have a hard time keeping my head up.

Come to my rescue and deliver me from the anxiety and depression I feel. They weigh me down every day and that makes me not want to face the world.

I will put my hope in you from this day forward. My eyes will be on you and your mighty power. Your praise will be on my lips and I will remember that you are my savior.

I will not allow disturbing thoughts to fill my mind but only those that build me up.

In Jesus’ name, I pray. Amen.

Also Related: 15 Prayers for Protection from- Enemies.

#5 Prayer for casting out a spirit of Fear.

2 Timothy 1:7 “For God has not given us a spirit of fear, but of power and of love and of a sound mind.”

Lord, you said you have not given me a spirit of fear, and today I cast it out of my life. I refuse to partner with the fearful thoughts it brings to my mind.

My mind is holy ground and I will only allow thoughts that are pleasing to you.

Forgive me for when I gave in to fear instead of trusting in you. Help me come to you in prayer instead of worrying about anything.

I reject anxiety and depression and declare they will not prevail over my mind.

I will guard my mind because I know the power it has over my life.

In Jesus’ name, I pray. Amen.

Anxiety and Depression
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#6 Prayer to trust in the Lord.

Proverbs 3:5-6 “Trust in the Lord with all your heart, And lean not on your own understanding; In all your ways acknowledge Him, And He shall direct your paths.”

Lord, thank you because you are my hope and salvation. You have given me life and have sustained me all these years.

Forgive me for when I try to make sense of many things in my life instead of trusting in you.

Show me how to trust in you on my darkest days when I’m surrounded by doom and gloom.

I know that you are the one with the truth and I can trust you to show it to me in every situation.

Help me stop worrying about the future but know that you are in control of it.

In Jesus’ name, I pray. Amen.

#7 Prayer to be anxious over nothing.

Philippians 4:6-8 “Be anxious for nothing, but in everything by prayer and supplication, with thanksgiving, let your requests be made known to God; and the peace of God, which surpasses all understanding, will guard your hearts and minds through Christ Jesus.”

Lord, your word has a solution for everything I face in life. Instead of worrying and being anxious, I will pray over everything that troubles me.

Today I hand over to you every situation that troubles me and trust that you can solve it.

I ask that you help me with the challenges I face in my family, work, goals, and relationships.

May your peace that surpasses all understanding guard my heart and mind and keep me from anxiety and depression.

In Jesus’ name, I pray. Amen.

#8 Prayer for deliverance from oppressive thoughts.

Psalm 9:9 “The Lord also will be a refuge for the oppressed, A refuge in times of trouble.”

Lord, I struggle with oppressive thoughts that leave me feeling anxious and depressed. My attempts to overcome them have failed. I come to you because you know how to help me.

Deliver my mind from dark thoughts that steal my joy. I take refuge in you because you are my strength. Teach me how to guard my mind and not allow thoughts that are not of you.

Help me check every thought against your word and let go of those that don’t align with it. I will fill my mind with hopeful thoughts that leave me feeling positive.

In Jesus’ name, I pray. Amen.

Also Related: How to get your Prayers Answered a Helpful Guide.

#9 Prayer to cast your cares on the Lord.

1 Peter 5:6-7 “Therefore humble yourselves under the mighty hand of God, that He may exalt you in due time, casting all your care upon Him, for He cares for you.”

Lord, thank you for always caring for me and showering me with your unfailing love. You are a loving Father and care about every aspect of my life, even the little things.

Your concern for my affairs comforts me because I know you will never leave nor forsake me.

I place myself under your care and trust that you will care for my needs. Help me not to worry about them because you have promised to provide for me.

I don’t have to worry and be anxious about how you will meet them.

In Jesus’ name, I pray. Amen.

#10 Prayer against worry.

Matthew 6:34 “Therefore do not worry about tomorrow, for tomorrow will worry about itself. Each day has enough trouble of its own.”

Lord, you are the God who has a plan for my life. It is a plan to give me a future and hope. I don’t have to worry because my life is in your hands.

You are in charge of my life and I will not worry about how it will turn out.

Help me not to worry about the troubles of today but to know you will help me handle them. You give me strength for each day and fill my life with your blessings.

Worry cannot add a day to my life and I banish it from my mind.

In Jesus’ name, I pray. Amen.

Photo by Kat Jayne from Pexels

#11 Prayer against a troubled Heart.

John 14:1 “Do not let your hearts be troubled. You believe in God; believe also in me.”

Lord, you always comfort me when I go through troubling times. You have promised to deliver me from all my troubles so I may live an abundant life.

My heart is troubled today because of the issues in my life. I don’t know how to deal with them and I am filled with troubling thoughts.

I will believe in your mighty power to save me because you are my savior. You are my strength and hope and because of you, I can look forward to better days.

Help me trade my troubling thoughts with your word which is the truth. I will guard my heart against evil.

In Jesus’ name, I pray. Amen.

#12 Prayer for a Cheerful Heart.

Proverbs 17:22 “A cheerful heart is good medicine, but a crushed spirit dries up the bones.”

Lord, I praise you because you are all-knowing and all-powerful. There is no other God like you. My spirit is crushed because of many things happening in my life.

I feel hurt and depressed and don’t know where to turn for help.

My eyes are on you because you are the only one who can help me get through the pain I feel. Give me a cheerful heart that will bring health to my mind and body.

My troubles have made me feel weak and afraid. May your words bring health to me and fill me with cheer.

Grant me your joy and gladness so I will walk with confidence knowing all shall be well.

In Jesus’ name, I pray. Amen.

#13 Prayer for joy in your Spirit.

Philippians 4:4 “Rejoice in the Lord always. I will say it again: Rejoice!”

Lord, thank you for helping me whenever I have struggles and challenges. It is hard for me to feel your joy because of a heavy heart.

Today I ask you to help me rejoice despite the things I am going through in my life.

Grant me the grace to rejoice knowing my troubles will be gone tomorrow. You promised that you will make all things work together for my good.

That’s enough to make me rejoice because you have defeated the enemy in my life.

In Jesus’ name, I pray. Amen.

In closing

You can overcome anxiety and depression with God’s help. He has the solutions for what you are worrying about all day.

According to Laurie Coombs, when we let the light of Christ shine into our hearts and minds, we will most definitely see darkness flee.

Prayers for Anxiety and Depression Resources.

Below are books you can read on how you can deal with the anxious and depressing thoughts you feel.

  1. Overcoming Anxiety and Depression by Bob Phillips
  2. When the Darkness Will Not Lift by John Piper
  3. Battlefield of the Mind by Joyce Meyer
  4. Spurgeon’s Sorrows by Zack Eswine

Here’s an inspiring quote on anxiety.

“Anxiety does not empty tomorrow of its sorrows, but only empties today of its strength.”

 ~ Charles Spurgeon


Is an Ordained Minister and Life Coach. He is an ordained minister since 1988. Shortly after receiving Jesus as his personal savior, he answered the call to ministry.

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