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Prayers for Desperate Situations: 17 Powerful Prayers

Prayers for Desperate Situations: 17 Powerful Prayers

When you are in a desperate situation, know that the challenges are not sent to destroy you, they are sent to strengthen you and God will always make a way for you out of desperate situations.

1 Corinthians 10:13, “No temptation has overtaken you except what is common to mankind. And God is faithful; He will not let you be tempted beyond what you can bear. But when you are tempted, he will also provide a way out so that you can endure it.”

When the going gets tough, you can find comfort by turning to the bible which is filled with words of wisdom, encouragement, and motivation.

God is concerned about what we are going through at each point of our lives, and He asked us to always come to Him as it is written in Matthew 11:28 (NIV) “Come to me, all you who are weary and burdened, and I will give you rest.”

Below are 17 powerful Prayers for Desperate Situations that will turn around any hopeless situation.

1. Prayer for Desperate Situation.

Isaiah 41:10 (NIV): So, do not be afraid, for I am with you, do not be dismayed, for I am your God. I will strengthen you and help you, I will uphold you with my righteous right hand.

Master Planner, You created my inmost being, You knit me together in my mother’s womb.

My frame was not hidden from You when I was made in the secret place when I was woven together in the depths of the earth. I praise You because I am fearfully and wonderfully made, Your works are wonderful, and I know that full well.

Lord, I live in a troublesome world that demands that I go through it with strength. I cannot give myself the strength I need or hold my head and walk confidently in desperate situations.

I ask for endurance to walk forward even during desperate situations. I depend on you heavenly father to give me the strength I need.

Beautiful God, You reminded me in comforting words that You will always be with me. You encouraged me not to be afraid and to put my faith in You in trying situations.

Lord, put your righteous hand on my shoulder and make me stand firm. Make me realize that I am not alone in any situation I might find myself in.

Lord, You are my companion as I go through trials and challenges in various aspects of my life and desperate situations. Strengthen me and uphold me Lord when nobody can as my feet are weak and my mind is tired in Jesus’ mighty name, Amen.

2. Prayer for Hopeless Situation.

Philippians 4:6-7 (NIV): 6 Do not be anxious about anything, but in every situation, by prayer and petition, with thanksgiving, present your requests to God. 

And the peace of God, which transcends all understanding, will guard your hearts and your minds in Christ Jesus.

Hide your face from my sins and blot out all my iniquity. Do not cast me from your presence or take your Holy Spirit from me. Create in me a pure heart, O God and renew a steadfast spirit within me, and restore to me the joy of your salvation.

The Chief Cornerstone, the bible said in Deuteronomy 31:8 that the Lord will go before me and be with me and will not leave me or forsake me.

I will not be dismayed because the Lord is with me. Just as you swore to never desert the people of Israel, You will never leave me or forsake me because I am in Christ.

As I wait patiently for You, the Righteous Judge in this hopeless situation, incline to me and hear my cry. Draw me out from this pit of destruction and set my feet upon a rock, making my steps secure. Put a new song in my mouth O God, a song of praise to you, my God.

Hear my cries and see my tears, savior. Do not ignore me or delight in my suffering. Respond to my pleas for mercy O Lord, in this hopeless situation. You are a loving and merciful father, go ahead of me and clear a way for me.

Lord, Your grace is sufficient for me, even in my deep, darkest times. Amen.

3. Prayer for Desperate Cases.

John 16:33 (NIV): I have told you these things, so that in me you may have peace. In this world, you will have trouble. But take heart! I have overcome the world.

The Comforter, Your commands are radiant, giving light to my eyes. The fear of You Oh Lord is pure and enduring forever.

They are more precious than gold, they are sweeter than honey. May these words of my mouth and this meditation of my heart be pleasing in your sight Lord.

Lord Jesus, when you were in the world, You suffered, and You said that anyone that will carry Your cross will suffer too.

You also said that I will rejoice after mourning for a while, and You will send the Holy Spirit to comfort and guide me. Therefore, I ask for the comfort of the Holy Spirit in this desperate case that has defied human intervention.

The word of God assures me that when I go through the deep waters, God will be with me and when I go through rivers of difficulty that I will not drown.

Righteous Father, You hear your people when they call to You for help. Lord, rescue me from all the deep and difficult waters of life that am passing through now.

Way maker, You always provide a way to overcome difficult situations. Your ways are not my way and what I cannot logically perceive You can easily explain.

Almighty Father, make a way for me and open new doors for me. Make me understand that whatever I may be passing through that You are always with me and will never forsake me in my time of need, Amen.

4. Prayer for Difficult Situations.

1 Peter 5:7 (NIV): Cast all your anxiety on Him because He cares for you.

Independent of who I am; rich or poor, educated or uneducated, I will meet difficult situations in life. Lord, lay a strong conviction in my heart that You who created me will be with me during happy times and times of sorrow.

Hold my hand and walk with me for You know how to lead. Lord, give me the right words and fill me with wisdom to manage this difficult situation.

The Bible says in Jeremiah 29:3 (NIV), “You will seek me and find me when You seek me with all your heart.”

Invisible God, I seek You with all my heart and soul, listen to my cries for the plea, and answer them. Wipe away all my tears and do not ignore this humble prayer for deliverance from every difficult situation.

Dearest Jesus, You know what I am passing through right now. I believe You can calm this current storm that I am going through. Make me stop looking at this situation and look up to you to give me hope. Thank You for Your love and care for me.

Author and Finisher of my faith, I hold on to Your promise in the bible which says that all things work together for good to those who love God (Romans 8:28), and decree that everything is working for my good.

Lord, bring peace, and joy and release me from all my problems. Bless me and make me a blessing to many in Jesus’ most precious name I pray, Amen.

 Desperate Situations

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5. Prayer for Impossible Situations.

Romans 8:18 (NIV): I consider that our present sufferings are not worth comparing with the glory that will be revealed in us.”

I will praise You, Lord, with all my heart. I will bow down toward Your holy temple and will praise Your name for Your unfailing love and your faithfulness. Thank You for You answer me when I call and greatly emboldened me.

I come before You today to present my prayer and petition to You with thanksgiving. Lord, let Your peace which transcends all understanding guard my heart and mind in Christ Jesus to remove all anxiety about any impossible situation.

Sovereign Lord, You have made the heavens and the earth by Your great power and outstretched arm. Lord, Your ways and plans are mysterious, but Your heart is trustworthy. I lay aside my fears and put my trust fully in You for nothing is too hard for You to do.

Impossibility Specialty, I understand that sometimes You allow impossible situations for Your purposes and our good. You have been faithful and have moved mountains of impossibilities in the past and will not change in this impossible situation. Lord, it may look impossible to me, but I know that with You all things are possible.

The Bible says in Luke 18:27, that what is impossible with man is possible with God. Thank You Jesus for reassuring me that even though my situation may be impossible for me, it is not impossible with You. Amen.

Also See: Prayer to God for Help: 15 Powerful Prayers.

6. Prayer in Hopeless Situations.

Jeremiah 29:11 (NIV): “For I know the plans I have for you” declares the Lord, “Plans to prosper you and not to harm you, plans to give you hope and a future.

Lord, keep me in perfect peace as my mind is steadfast in You and because I trust in You. I will trust in You forever for you Lord the Rock Eternal and Rock of Ages. You, Lord, are my strength, my Defenses, and my Salvation.

My Comforter, the bible says in Isaiah 40:31 that those who hope in the Lord will renew their strength. They will soar on wings like eagles, they will run and not grow weary, and they will walk and not faint. I stand on this word of God and declare that this is my portion in this hopeless situation.

Lord, my heart searches for Your comfort in this hopeless situation. As I get torn by a lack of hope for the future and feel utterly helpless, Lord comfort me and gives me new hope. Amidst this storm Jesus, fill my heart with calmness and comfort that can only come from you.

Jesus, with You in my life, I will never face any problems alone and I will know victory instead of failure. Lord, as I stand with You, guide me through this hopeless situation in a way that is far better than I can imagine or think.

Put my life together and walk with me step by step in Jesus’ name, Amen.

7. Prayer for Desperate Times.

Psalm 9:9-10 (NIV): The Lord is a refuge for the oppressed; a stronghold in times of trouble. 10 Those who know Your name trust in You, for You Lord, have never forsaken those who seek You.

If it had not, been You Lord, who has been on my side, then when men rose against me, they would have swallowed me up quickly, when their wrath was kindled against me. Blessed be the Lord, who has not given me up as prey to their teeth. My help is in the name of the Lord, who made heaven and earth.

Everlasting God, You said that I should call on You in the day of trouble. I am before You, crying out to You with all my energy and strength hoping for intervention, healing, and comfort in these desperate times.

Keep track of all my sorrows, collect all my tears in your bottle and record each in your book. Address the cause of my tears and sorrow, my Rock. I cannot rely on my thoughts and actions. I choose to surrender them to you, and I ask You to lead me.

Cause me not to lose heart, though outwardly I am wasting away, yet inwardly I am being renewed day by day. Lord, make me fix my eyes not on what is seen but on what is unseen, since what is seen is temporary but what is unseen is eternal, Amen.

8. Prayer for Desperate Need.

James 1:2-3 (NIV): Consider it pure joy, my brothers and sisters, whenever you face trials of many kinds 3 because you know that the testing of your faith produces perseverance.

You are the God who performs miracles; You display Your power among the people. Lord, thank You for displaying Your divine and miraculous power amongst all people. I believe in Your power in my life in this desperate need.

Lord, You are gracious and compassionate, You provide for those who fear You, make provisions for me. You remember Your covenant forever and have shown Your people the power of Your work, bringing that same power into my need.

In Jeremiah 32:7, You said that You are the God of all mankind. Is anything too hard for You? You are an amazing God and there is nothing too hard for You. Lord, whatever darkness and desperate needs that try to hide my joy and happiness, I will not be afraid for Your light is the lamp to my feet.

Righteous Judge, my faith is like the size of a mustard seed; assist me where there is any doubt. In Your Name, I ask this desperate need to be moved from here and never to return.

Luke 1:37 said that for no word from god will ever fail, therefore, no word from You will ever fail and I declare Your great and powerful word over my desperate need, Amen.

9. Prayer for Broken Hearted.

Psalm 147:3 (NIV): He heals the brokenhearted and binds up their wounds.

Lord, forgive my transgressions and cover my sins. Do not count my sins against me and remove every form of deceit from my spirit.

Wisdom of God, You are my hiding place, protect me from trouble, and surround me with songs of deliverance. Instruct and teach me in the way that I should go, counsel, and watch over me.

The hope of Glory, thank you for Your sacrifice and loving me so much when You suffered heartbreak for my sake on the cross of Calvary. Give me the strength to keep my eyes on You during dark days.

Take this pain of broken heart from me and use it for Your good. Let me find myself closer to You than ever before in this trying time.

Matthew 11:28 says, “Come to me, all you who are weary and burdened, and I will give you rest.” God, You are my refuge and strength, an ever-present help in trouble. as I lay every burden and sorrow on Your feet, give me rest and calmness that can only come from You.

Wipe every tear from my eyes, let there be no more death or mourning or crying or pain, for the old order of things has passed away in my life. You came to set me free and to show that not even death can defeat me.

Take away this pain of a broken heart and visit me with renewed strength, soft wisdom, and stirring of hope, Amen.

10. Prayer for Desperate Help.

Philippians 4:13 (NIV): I can do all this through Him who gives me strength.

Lamb of God, I know what it is to be in need, and I know what it is to have plenty. Teach me the secret of being content in any and every situation, whether well-fed or hungry, whether living in plenty or want. Give me the grace that is in Christ Jesus in this situation.

You told me to ask, and it will be given to me, and should seek and I will find, I ask for help in this situation. Let every locked door against me be opened and let answers and help be given unto me.

Help me Lord my God, for I rest on You and in Your name as I go against every tribulation of this world. You are my God and do not let man prevail against me.

You are not a High Priest who cannot sympathize with our weaknesses but was in all points tempted as we are. I, therefore, come boldly to the throne of grace, that I may obtain mercy and find grace to help in time of need.

The Bible assured me that God will never leave me nor forsake me. So, I boldly say that the Lord is my helper, and I will not fear. I need Your help desperately because I am poor and needy. Look upon me with mercy and kindness. Do not delay Oh Lord my God because You are my deliverer.

11. Desperate Prayer Request.

Psalm 50:15 (NIV): and call on me in the day of trouble, I will deliver you, and you will honor me.

Heavenly King of Glory, The Great God, Master of the Universe, I thank You and glorify Your great name. I bow before Your Holy throne in worship and adoration.

Lord God Almighty, I come before Your Holy presence desperately seeking Help. Your words make me know that You will never leave me nor forsake me.

Heavenly Father, I pray that You assure me of Your love; take away my fear and shame. Blunt the assaults of the devil and his agents against my life. Help me Lord to face my life’s challenges and surround me with the love and care of Your Holy Spirit.

My God, I desperately need Your help in these perilous times. I know that the devil is prowling about like a wounded lion seeking souls to devour.

Save me from satanic snares Oh Lord, protect me from all the vices of Stan, and may the plans of the enemies never come to manifestation in my life. I plead that the blood of Jesus Christ covers me, now and always, Amen.

Prayers for Desperate Situations

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12. Prayer for Desperate Financial Help.

Philippians 4:19 (NIV): And my God will meet all your needs according to the riches of His glory in Christ Jesus.

Gracious God, how great Thou art! You are my Eternal Rock of Ages; I worship and adore You. I thank You for the wonderful deeds You do in my life, Your countless blessings, Your divine mercies, and Your great provisions. You are mighty Lord, and I worship Your Great name.

Heavenly Father, I come before Your throne of mercy, praying for financial help. Lord, Your plan for us is to prosper above all things, even as our soul prospers. Anoint my head Lord, with your oil of prosperity; cause people of all nations of the world to enter my life and bless me financially.

Merciful Lord, uproot poverty and all its likes from my life and destiny. Connect me Lord with people who have the right information that will push me to the next level of financial wealth and prosperity, and those who will advance my destiny in life.

Gracious God, I pray that You neutralize every evil money that is destroying my finances and let the blood of Jesus Christ be released to repair every faulty foundation in my life and destiny.

Lord, please enlarge my coast and cancel every evil trap of poverty in my life. Provide for me speedily Lord, so that lack of finances will not delay Your purpose for my life, nor limit the manifestations of my dreams and visions, Amen.

13. Miracle Prayer for Desperate Situations.

Romans 8:28 (NIV): And we know that in all things, God works for the good of those who love him, who have been called according to his purpose.

My All-Sufficient God, The Lion of the Tribe of Judah, I come before Your awesome presence with joy and thanksgiving. I bow before Your throne of mercy, and I worship You.

My Great Provider, the situations of life are wearing me down and making me lose my trust in You. Lord, I feel helpless in the face of my circumstances. I am weighed down by uncertainties and the negative happenings around me and in my life.

Gracious Lord, cause Your merciful countenance to fall upon me and let Your light shine upon me. Father, send help from heaven and deliver me from my challenging and life-threatening situations.

I am desperate Lord, please hear and answer my prayers speedily, and let Your miracle locate me. With man, this may be impossible, but with God, all things are possible.

Please, Lord, make all my plans succeed, clear away all my life’s obstacles, make my path smooth, and speedily hear my prayers, as You deliver me from challenging situations in my life, Amen.

14. Uplifting Prayer for Desperate Situations.

Mark 9:23 (NIV): If you can? said Jesus, “Everything is possible for one who believes.”

Gracious God, how great Thou art. You are greatly to be praised. I bow before Your Holy temple, and I worship and adore You. I thank You because Your strong right hand always lifts me to a place of security.

Eternal King of Glory, life’s situations are taking a great toll on me, especially making me waver in my faith in You. It makes me question Your love and mercy in my life.

My Lord and My Maker, You are the lifter of my soul, I raise a holy lamentation unto You; I pray for Your divine upliftment in the face of my desperate life’s situations.

Constantly remind me of Your boundless love towards me and to all mankind. Always make me remember that You are always with me, even as I face life’s most difficult challenges.

Lord Jesus, shedding Your blood on the Cross of Calvary for my sake and motivation is a perfect show of love that You have my best interest at heart, and You will never forsake nor leave me.

As I go through travails and challenging situations in life, may I always be reminded in my heart that You love me absolutely and You are always with me.

My Good Shepherd, I know that You are always walking close beside me in my times of distress, and despair and as I walk through the dark valley. You are the Lifter of my head Lord, and I am assured that Your goodness and unfailing love will always be with me all the days of my life, Amen.

15. Powerful Prayer in Desperate Times of Need.

Deuteronomy 31: (NIV): The Lord himself goes before you and will be with you; He will never leave you nor forsake you. Do not be afraid; do not be discouraged.

Oh, Ancient of Days, I worship and glorify Your Holy Name. I join my voice with the heavenly hosts and sign of Your greatness and majesty. You are worthy of my praise Lord, and I return all the praises and adoration unto You.

Most gracious God, my Helper in times of need, I have come before You in this moment of need seeking Your mercy and deliverance. Merciful Jesus, I have exhausted all my options, and everything I am holding unto has failed.

I pray that You unleash your great power unto my life’s darkest hours and show Yourself mighty and strong in my life.

Almighty God, hear my cries and remember Your promises which assure me that You never turn away desperate; You never ignore my cries. Lord, I have the assurance that the dreams and visions You have placed in my life will come to pass.

Therefore, I desperately and earnestly beseech You to hear my prayers and deliver me from these desperate times of need. Give me the grace to persevere in prayer no matter what I face in life, how bad things may look, or what situation I find myself in, knowing fully well that You have the final say over my life, Amen.

16. Desperate Prayer for Desperate Times.

Joshua 1:9 (NIV): Have I not commanded you? Be strong and courageous. Do not be afraid; do not be discouraged, for the Lord Your God will be with you wherever you go.

Righteous Father, Helper of the helpless, Deliverer of those who are in need, I thank you for Your countless blessing upon my life. These are sobering times that we live in today.

Lord, life’s circumstances have made me miserable and have put me in a state of despair. I implore You Oh Lord to bring visible and speedy help to me in these desperate times.

Come to my assistance in this great need, that I may receive the consolations and succor of heaven in all my necessities, tribulations, and sufferings. Give me the grace Lord to be utterly dependent upon You in these desperate times.

Your word in Psalm 50:15 says, “And call on me in the day of trouble, I will deliver you, and you will honor me.” Father, I desperately call upon You in this desperate time of need, deliver me Oh Lord, and I will continue to honor you all my life.

Your word still assures us in Isaiah 65:24, “Before they call, I will answer, while they are still speaking, I will hear.’ in this, my time of need Lord, speedily hearken unto my prayer, and grant me all my heart desires, Amen.

17. Desperate Prayer for Comfort.

2 Corinthians 1:3-4 (NIV): Praise be to the God and father of our Lord Jesus Christ, the father of compassion and the God of all comfort 4 who comforts us in all our troubles so that we can comfort those in any trouble with the comfort we ourselves receive from God.

Almighty ever Living God, Master of the universe, I bow down before You, and I worship You. I thank You for Your wonderful grace and mercies upon my life. I thank You because You are my Sufficient and All-Powerful God. You are my succor in times of distress and my comfort in times of despair.

Heavenly Father, this world is filled with so much chaos and struggles. I ask for Your comfort to experience everlasting peace. Dear God, take hold of my broken heart and anxious thoughts about my uncertain future.

Give me comfort and allow me to find rest in Your everlasting arms of mercy. Send your steadfast love and Holy Spirit to guide me through my present discomfort.

Have compassion on my weary soul and be my great comforter during these difficult times. I am presently burdened with fear, troubled feelings, pains, family burdens, and weakness.

Grant me comfort Oh Lord, and let Your blessed presence give me succor. Lord, everything seems to be falling in around me, the walls seem to be closing in on me, nothing in this world seems to hold any hope, and everything looks completely hopeless, but one thing I know is that You are not ever caught by surprise.

You will always save those who are Yours from calamity according to Your word in Hebrew 7:25.

Let Your perfect peace and grace fill my spirit during these uncertain times, and may I find comfort in Your Holy name as I no longer fear as I walk through the darkness of this world, knowing Your presence is with me, Amen.


Brethren, be strong and courageous, for He that has called us can save too the uttermost those who come to God through Him since he always lives to make intercession for you (Hebrew 7:25).

Also remember that your hardest times often lead to the greatest moments of your life. Keep the faith and run the race. It will all be worth it in the end. Please share these prayers for desperate situations with your family and friends.

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