15 Amazing Prayers for Someone with Depression

Depression is like a disturbing demon that attacks every time you are at your weakest. It is a mental torment that conspires with lying spirits to oppress.

Talk of the episodes that strike when you least expect. Sometimes, the weight it brings on your emotions and decisions is overwhelming.

Depression is an evil spirit that takes you away from your real self and the real world. But the good news is that God has given us control over it.

Through the power of prayer, you have been given the authority to bind every spirit of heaviness. Depression is powerless when you commit yourself to a life of prayer.

In this article, I will share 15 prayers for someone with depression. Let these prayers be a starting point for you to bind and overcome every depressive thought.

Below are 15 Amazing Prayers for Someone with Depression.

1. Prayer for Someone with Depression.

Dear Lord,

I come before You today to surrender every burden in my mind. I lay down every burden that causes oppression of the mind.

Your Word in Matthew 11:28-39 (KJV) says, “Come unto me, all ye that labor and are heavy laden, and I will give you rest. Take my yoke upon you, and learn of me; for I am meek and lowly in heart: and ye shall find rest unto your souls. For my yoke is easy, and my burden is light.”

I ask You to grant me rest from every burden that makes me restless. If there are burdens I am carrying in my heart, mind, and soul, I lay them before you today.

I replace them with Your yoke of healing, peace, and comfort. As I lift up this prayer for someone with depression, may I find complete healing in You.

In Jesus’ name, I pray. Amen.

2. Prayer for a Loved One with Depression.

Mighty Father,

I praise You for You are more powerful than depression and every mental health condition. I lift up my heart to pray for my loved one who is battling against depression.

Your Word in James 5:16 (KJV) says, “Confess your faults one to another, and pray one for another, that ye may be healed. The effectual fervent prayer of a righteous man availeth much.”

As I pray this prayer for someone with depression, I ask You to release healing and peace upon them. Father, let power flow through this prayer and cover their mind. I bind every spirit of darkness that has taken over their thoughts.

In the name of Jesus, I cast out every spirit of heaviness, bitterness, unforgiveness, and trauma. I ask You to set them free from mental bondage and captivity by the power of the Holy Spirit.

In Jesus’ name, I pray. Amen.

3. Deliverance Prayer for Someone with Depression.

God of deliverance,

I come before You to pray for deliverance from the stronghold of depression.

I stand in the authority of Jesus Christ to bring down every stronghold the enemy has built. By the power of the Holy Spirit, I cast down every demonic stronghold that makes me find no inner peace.

Your Word in 2 Corinthians 10:5 (KJV) says, “Casting down imaginations, and every high thing that exalteth itself against the knowledge of God, and bringing into captivity every thought to the obedience of Christ.”

I cast down every evil imagination, every fear, and every oppressive thought. Father, I bring my mind into captivity with Your obedience.

As I surrender my life through this prayer for someone with depression, let every thought in my mind be life-giving.

In Jesus’ name. Amen.

4. Prayer against Isolation for Someone with Depression.

Heavenly Father,

I invite You to comfort and surround me with Your presence. This depression is deceptive; it seeks to push me away from the people around me.

The lying spirits speak to my mind, telling me to isolate myself from everyone and stay behind closed doors. I refuse to allow it to separate me from the world and from the people who comfort me.

Lord, fill me with the Holy Spirit, my Comforter, to comfort me in this trying time. I don’t want to feel alone, rejected, unloved, and neglected.

Your Word in Psalm 34:18 (KJV) says, “The Lord is nigh unto them that are of a broken heart; and saveth such as be of a contrite spirit.”

I ask You to draw near to me and be my friend. Surround me with good people who will encourage and support me in this journey.

In Jesus’ name. Amen.

5. Prayer against Suicidal Thoughts for Someone with Depression.

Dear Lord,

I welcome You to reign over my life, especially my thoughts. Depression has a way of corrupting thoughts and killing people’s self-esteem. It fills my mind with thoughts of unworthiness and hopelessness.

Sometimes, these thoughts are suicidal. The spirit of depression tells me that death is a better option, that I’m insignificant in this world. But today, I stand in opposition against this spirit in Jesus’ name.

I silence and cast down every suicidal thought that leads me into the valley of the shadow of death. Your Word in Ecclesiastes 7:17 (KJV) says, “Be not over much wicked, neither be thou foolish: why shouldest thou die before thy time?”

I refuse to allow depression to rob my life before my time. It will not lead me to foolishness and wickedness in Jesus’ name. Amen.

6. Prayer for Complete Healing for Someone with Depression.

Almighty God,

You are the healer of all diseases and health conditions. I lift up this prayer for someone with depression to pray for complete healing. Sometimes, I suffer frequent anxiety attacks.

There are times when I experience seasonal and emotional episodes. This is always painful, overwhelming, and sorrowful. I don’t want to experience a depression attack ever again.

Your Word in Jeremiah 33:6 (KJV) says, “Behold, I will bring it health and cure, and I will cure them, and will reveal unto them the abundance of peace and truth.”

Father, I long to experience everlasting peace and prosperity. I ask You to touch me a second time and bring total healing upon my mind.

May I enjoy health in abundance both now and forever more. Amen.

7. Prayer for Compassion.

Compassionate God, sometimes it is hard for anyone to convince me that they love me. Other times, I feel You are distant from me and I don’t even feel Your love.

Yet, I know that Your love for me is unconditional and everlasting. I ask You to pour out Your love upon me. Soak me, O God, in the spring of Your love.

Your Word in Jeremiah 31:3 (KJV) says, “I have loved thee with an everlasting love: therefore with lovingkindness have I drawn thee.”

Let me experience Your lovingkindness in a way that will bring healing and peace upon me. As I pray this prayer for someone with depression, may Your love drive out every depressive thought.

In Jesus’ name, I pray. Amen.

8. Prayer for When You are Overwhelmed with Depression.

My Father in Heaven,

I feel overwhelmed, crushed, drained, and perplexed. I have no one else to run to for help and comfort but You. You sustain me in moments when I feel weak and shaken beyond my ability by this mental condition.

So, I lean on You, and I surrender every aspect to Your hands. I welcome You to have Your way in this overwhelming situation.

Your Word in Psalm 55:22 (KJV) says, “Cast thy burden upon the Lord, and He shall sustain thee: He shall never suffer the righteous to be moved.”

I refuse to be moved or shaken by depression, so I cast it upon You. In this moment of prayer for someone with depression, let me find rest and healing.

In Jesus’ name, I pray. Amen.

9. Prayer for the Light of God for Someone Battling Depression.

Dear Lord,

I come before You today to seek Your light and direction. Depression clouds my mind, heart, and soul with total darkness. I try to look ahead of me but I can’t see anything.

It drowns me in a pit full of darkness and blinds me to the future ahead of me. But I find hope in You, the God of light, clarity, and direction. I ask You to light my path, mind, and life, and show me the way.

Your Word in John 1:4-5 (KJV) says, “In Him was life; and the life was the light of men. And the light shineth in darkness; and the darkness comprehended it not.”

Father, shine Your light upon my life, so bright that the darkness of depression cannot overcome it. I call upon You to cast out every spirit of darkness and usher me into Your light.

In Jesus’ name. Amen.

10. Prayer for Strength for Someone with Depression.

Almighty God,

When I feel weak, shattered, and depressed, be my strength. I bow before Your throne to ask You to strengthen me in my weakness.

Your Word in 2 Corinthians 12:9 (KJV) says, “My grace is sufficient for thee: for my strength is made perfect in weakness. Most gladly therefore will I rather glory in my infirmities, that the power of Christ may rest upon me.”

When depression drains my strength, let Your Spirit renew it and make me stronger than before. Perfect Your power, O God, in my weariness so that I can soar above the heaviness caused by depression. I seal this prayer for someone with depression, with faith and hope.

In the name of Jesus, I pray. Amen.

11. Identity Prayer for Someone with Depression.

Heavenly Father,

I thank You for giving me an identity in You. Thank You for making me Your own through Christ. Depression has a way of ruining my sense of identity; it makes me feel lost and neglected. But I know that You love, cherish, and value me as Your own.

When the enemy tries to tell me that I am a nobody, remind me that I matter to You. Your Word in Ephesians 2:10 (KJV) says, “For we are His workmanship, created in Christ Jesus unto good works, which God hath before ordained that we should walk in them.”

Father, let no spirit or depressive thought change the way I see myself, for I am created for good works. I am Your workmanship, and this is what will always matter to me no matter how intense it gets.

In Jesus’ name. Amen.

  12. Prayer for Courage.

Dear Lord,

I pray for the courage to face fears, anxieties, worries, and every depressive thought. In this prayer for someone with depression, I ask You to empower me to be courageous and bold.

I pray for the courage to acknowledge my need for help, support, and deliverance. Your Word in Psalm 31:24 (KJV) says, “Be of good courage, and He shall strengthen your heart, all ye that hope in the Lord.”

Father, grant me the courage to hope in You for better days ahead. I call upon You to help me be of good courage, to fight this battle courageously, and to overcome.

In the powerful name of Jesus, I pray. Amen.

13. Prayer for Joy for Someone with Depression.

Everlasting God,

I seek refuge and safety in Your shelter. I ask You to draw closer to me so I may dwell in Your presence. As I pray this prayer for someone with depression, I hope to find joy in You.

Your Word in Psalm 16:11 (KJV) says, “Thou wilt shew me the path of life: in thy presence is fulness of joy; at thy right hand there are pleasures for evermore.”

Father, fill my heart with joy and happiness that depression cannot snatch away. I call upon You to cast out every spirit of sorrow and mourning. May my cup of joy overflow both now and forevermore.

In the mighty name of Jesus, I pray. Amen.

14. Prayer for a Renewed Sense of Purpose.

Almighty God, I thank You for creating me for a good and divine purpose. I know fully well that my life is meaningful. Depression may try to shift my focus from my true purpose, but I believe Your purpose will prevail.

Your Word in Psalm 138:8 (KJV) says, “The Lord will perfect that which concerneth me: thy mercy, O Lord, endureth forever: forsake not the works of thine own hands.”

Father, I know that even amid this battle with depression, You will fulfill Your purpose for me. Let me not wander off from the path You have for me.

In Jesus’ name, I pray. Amen.

15. Prayer against Generational Depression.

Dear Lord, my Redeemer, and Deliverer, I cry out to You for deliverance from generational patterns of depression. I break every ancestral chain and every recurring pattern of mental breakdown.

In Jesus’ name, I refuse to suffer the mental challenges that my forefathers suffered. Your Word in Romans 8:2 (KJV) says, “For the law of the Spirit of life in Christ Jesus hath made me free from the law of sin and death.”

I choose to walk in this freedom of the Spirit of life. Father, delink me from every genetic connection and linkage that makes me a victim to depression.

As I pray this prayer for someone with depression, make me a new creation in Christ.

In Jesus’ name. Amen.

Conclusion

Depression must be defeated; and the best way to defeat it is through the power of prayer. If you feel like you are experiencing any form of mental oppression, don’t wait for it to get worse.

Go on your knees and pray these prayers for someone with depression. Through them, rebuke every spirit of depression and declare your freedom from mental bondage.

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