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15 Powerful Prayers to Get Out of Depression

15 Powerful Prayers to Get Out of Depression

Are you tired of being depressed? Do you want to get out of depression?

These powerful prayers will help you to get out of depression. God has your back, the things we can’t possibly do for ourselves are the same thing he does effortlessly for us, and that includes getting out of depression and worry.

If you’re feeling the severe weight of depression today or if you’ve been battling with it for some time, pray these powerful prayers to get out of depression.

As you pray, remember to give it all to God and wait in earnest expectation because He will give you peace and rest.

Here Are 15 Prayers to Get Out of Depression.

#1. Prayer to Get Out of Depression.

Deuteronomy 31:8 – The Lord himself goes before you and will be with you; he will never leave you nor forsake you. Do not be afraid; do not be discouraged.

Dear Father God, You know how I have been suffering from anxiety disorder and depression. So, I’ve come to ask that You help me find the appropriate medical attention that will help me to get out of this depression.

Dear Lord, please give me the courage and strength to deal with the suffering of this stressful feeling.

Holy Spirit, guide me through Your love to overcome this gloom and sadness. In Jesus’ name, I pray. Amen

#2. Prayer to Battle Depression.

Philippians 4:13 – I can do all things through Christ who strengthens me.

Dear Heavenly Father, thank You for Your unchanging nature. The despondency and unhappiness that I feel is so overwhelming, it appears the devil is trying all he can to break me.

Therefore, I ask that You please sustain and protect me. Help me to get out of this melancholy and despair and enable me to stand.

As a result of everything that I’m battling with, I’m struggling physically, emotionally, and spiritually. Abba Father, right now, I’m receiving all kinds of negative emotional signals, hence I need you more than ever.

Please come to my rescue because You are the only One who can really help me. In Jesus’ name, I pray. Amen.

#3. Prayer for Finding the Cause of the Depression.

John 16:33 – I have told you these things, so that in me you may have peace. In this world, you will have trouble. But take heart! I have overcome the world.

Almighty God, the hollow feeling and dejection in my heart is becoming something I can’t handle anymore on my own. But the part that is most heartbreaking Lord is the fact that I don’t know what is responsible for how I feel.

Hence, I ask that You reveal what is responsible for these depressing feelings. Lord, also show me if the depression I’m experiencing now is a result of a spiritual battle.

Father, if it is, I pray that You bring it to light, and You will also help fight it to a standstill. In Jesus’ name, I pray. Amen.

#4. Prayer for Help.

Jeremiah 29:1 – 1For I know the plans I have for you, declares the Lord, plans for peace and not for evil, to give you a future and a hope.

Dear Lord Jesus, thank You so much for understanding what I am currently going through because You also went through a harrowing experience like what I’m suffering right now.

Lord, I need Your help badly, so I ask that You please lead me to the right place where I will get appropriate help.

Thank You, dear Lord, because You will send me the right help in no time. In Jesus’ name. Amen.

#5. Prayer for Lonely Times.

Matthew 11:28 – Come to me, all who labor and are heavily laden, and I will give you rest.

Lord Jesus, thank You for reminding me how weak I am. I know You understand exactly how I feel at this moment because there were times too that You were grieved, distressed, and experienced deep sorrow and loneliness.

Gracious God, I feel very distressed because I’m afraid that I may not survive the anguish in my heart.

I need You as much as I need physical and emotional support, therefore I ask that You send me help.

Lord, I have grown so weary that I cannot bear this burden alone. I am in dire need of an extraordinary friend at this time, someone who can encourage, support, and remind me how strong I am.

Thank You because I know that You will give an answer to my supplication. In Jesus’ name, I pray. Amen.

Also Related: 28 Powerful Prayers for Anxiety and Depression.

#6. Prayer for Grace to Get Out of Depression.

Isaiah 41:10 – Fear not, for I am with you; be not dismayed, for I am your God; I will strengthen you, I will help you, I will uphold you with my righteous right hand.

Heavenly Father, thank You for allowing my weakness to manifest in the form of this depression that I am trying desperately to get out of.

Thank You so much too for Your grace that You have made sufficient for me even though I’m still struggling with desolation and indentation.

As such, I ask that You use this difficult time to help me get more intimate in my relationship with You.

I pray that You use this time to fix all that needs fixing in my life, even if it means me going through this depression.

Dear Holy Spirit, thank You because You will get the glory for everything that Your mighty hand will produce in me.  In Jesus’ name, I pray. Amen.

#7. Prayer for Strength Amidst Weakness.

Joshua 1:9 – Have I not commanded you? Be strong and courageous. Do not be frightened, and do not be dismayed, for the Lord your God is with you wherever you go.

My Father, thank You because no matter what the devil tries to say to me, I know I am not defined by this weakness because I am Your child.

Therefore, according to Your Word, I am defined by what Your Son, Jesus accomplished on the cross for me.

By the reason of You offering Your beloved Son up for me, I can face each day with fresh hope and grace.

So dear Lord, I ask that You help me focus on the things that are true, and not focus on what the devil says or how I feel.

Help me to gain a new appreciation for myself, so I can focus daily on my strength and not my weakness. In Jesus’ name, I pray. Amen.

#8. Prayer Against Depression.

Psalm 3:3 – But you, O Lord, are a shield about me, my glory,  and the lifter of my head.

Dear Heavenly Father, I ask that You encourage and strengthen my heart, especially now that the troubles of life are beginning to overwhelm me.

Guard my heart away from depression and give me the strength to rise up strong each day and fight against the struggles which are constantly seeking to weigh me down. In Jesus’ name, I pray. Amen.

#9. Prayer for When You Are in Darkness.

Psalm 40: 1-2: I waited patiently for the Lord; he inclined to me and heard my cry.

He drew me up from the pit of destruction, out of the miry bog, and set my feet upon a rock, making my steps secure.

Merciful God, the darkness of despondency has taken a stronghold on me and I can’t seem to find my way back to the light.

I earnestly need to escape from the darkness that has engulfed my heart. So I ask that You illuminate every darkness in it with the light of Your glorious presence.

Let it dispel every thought of death that constantly consumes me, I want to stop believing the lies of the enemy.

Hence, I ask that You remind me of the powerful truths in Your word which include: that I will not die but live.

You are with me when I feel alone. I am valuable and known by You even when I feel worthless. Help me never to forget any of these truths, in Jesus’ name I pray. Amen.

#10. Prayer to Escape the Pit of Depression.

Deuteronomy 31:8 – The Lord himself goes before you and will be with you; he will never leave you nor forsake you; do not be discouraged.

Dear Loving God, it appears my world has crumbled, hurling me into a deep, dark pit of desolation. So I have come to surrender this totally to You.

I feel desperate, helpless, and very afraid, and I ask that You please lift me out of this pit of depression and show me the way forward.  In Jesus’ name, I pray. Amen.

Also Related: 15 Prayers for Healing from Emotional Abuse.

#11. Prayer for the Will to Live.

Psalm 23:3 – He restores my soul. He leads me on the paths of righteousness for his name’s sake.

Heavenly Father, I often feel out of place in this world that You brought me into for many unexplainable reasons. I simply don’t fit in most of the time, as a result, I helplessly wish You take me away from this world.

However, I know this isn’t Your will for me, so I ask that You remind me that even though this world isn’t my home which is why I will never fit in here, my time here isn’t over because You have a plan and purpose for me.

Gracious God, I ask that You give me the desire to live. When I feel like I don’t matter at all, remind me that You created me for a divine purpose.

Dear Lord, when I don’t understand why I feel the way I feel – please remind me that You know and understand the depth of my pain.

Thank You, Father, because, despite the fact that You know how flawed I am, You still love me immensely. Amen.

#12. Prayer to Get Out of the Struggle With Depression.

Psalm 9:9 – The Lord is a stronghold for the oppressed, a stronghold in times of trouble.

Almighty and Everlasting God, You know how I am battling those inner demons of loneliness, hopelessness, unworthiness, and depression.

I pray that You shine the light of Your presence on me. Guide me to find happiness, contentment, and peace within myself in Jesus’ name I pray. Amen.

#13. Prayer for Winning the War Against Depression.

Psalm 23:4 – Even though I walk through the valley of the shadow of death, I will fear no evil, for you are with me; your rod and your staff, they comfort me.

Dear Loving God, thank You for being my everything, as such I can ask anything of You. I come to You in need of Your help to get out of the siege of depression and worry.

Father, replace my worry with rest. Help me to accept and enjoy the peace, love, and understanding that You offer, so I can finally win this war against depression, worry, and anxiety. In Jesus’ name, I pray. Amen.

#14. Prayer for God’s Help Out of Depression.

1 Peter 5:7 – Casting all your anxieties on him, because he cares for you.

Almighty God in Heaven, I come to You seeking Your help because You are my divine Helper.

I ask that You help me turn to You and not to myself, especially now that I’m battling depression. Help me to start doing more trusting and less worrying.

Holy Spirit, help me to rely on Your report because I know that they are good. In Jesus’ name, I pray. Amen.

#15. Prayer for Wisdom to Get Out of Depression.

Proverbs 3:5-6: Trust in the Lord with all your heart, and do not lean on your own understanding. In all your ways acknowledge him, and he will make straight your paths.

My Father in Heaven, You are the source of all wisdom, hence I ask that You give me wisdom to find a way out of this depression.

Hope to keep believing that You are working things out for my good and grace to enjoy the peace that You are bringing into my life. In Jesus’ name, I pray. Amen.


In addition to the above 15 prayers to get out of depression, the Scriptures attached to the prayers will help you overcome and get out of depression completely.

More so, they will help you find peace, joy and keep you encouraged in the midst of depressing circumstances and feelings.

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